Within each faction, Hellgate: London are two classes. Cabalists have the Evoker, a frail but powerful direct damage spellcaster, with few direct attacks but strong minions. Templars have the Guardian, a defensive class that receives bonuses for being surrounded, who can wield two swords and trades defense for damaging power. Finally, Hunters have the Marksman, and the Engineer, a high-tech version of the Summoner, using hovering attack bots and armed drones.

Each class has its own class-specific in Hellgate: London. Templar classes typically use Swords and heavy plate armour; Cabalist classes use "Focus Items", power gloves that allow one to cast spells; and Hunter classes rely on high-powered rifles and cannons, but have weaker armor in Hellgate: London.